Anti-Tubular Basement Membrane Antibody Nephritis Manifesting in a Patient With Chronic Lymphocytic Leukemia: A Very Rare Case Report.
J Investig Med High Impact Case Rep
; 12: 23247096241281612, 2024.
Article
in En
| MEDLINE
| ID: mdl-39315468
ABSTRACT
Anti-tubular basement membrane (anti-TBM) antibody nephritis is a rare type of tubulointerstitial nephritis associated with progressive decline in kidney function. It is characterized histopathologically by tubular atrophy and dilation, interstitial fibrosis, lymphocyte and macrophage-predominant cellular infiltration, and linear deposition of IgG and complement along the tubular basement membrane. We herein present a case of a 69-year-old male who was recently diagnosed with chronic lymphocytic leukemia (CLL) and was referred for evaluation of kidney failure, ultimately diagnosed as anti-TBM antibody nephritis progressing into end-stage kidney disease (ESKD). This case report highlights the management challenges of anti-TBM antibody nephritis as a rare kidney disorder.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Basement Membrane
/
Leukemia, Lymphocytic, Chronic, B-Cell
Limits:
Aged
/
Humans
/
Male
Language:
En
Journal:
J Investig Med High Impact Case Rep
Year:
2024
Document type:
Article