Transition-state alkylation geometries of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene enantiomeric isomers with nucleic acid dimers.

Kikuchi, O; Pearlstein, R; Hopfinger, A J; Bickers, D R

Kikuchi, O; Pearlstein, R; Hopfinger, A J; Bickers, D R.

J Pharm Sci ; 72(7): 800-8, 1983 Jul.

Article in En | MEDLINE | ID: mdl-6411894

Subject(s)

Benzopyrenes/metabolism; DNA/metabolism; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Alkylation; Chemical Phenomena; Chemistry, Physical; Nucleic Acid Conformation; Stereoisomerism

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Collection: 01-internacional Database: MEDLINE Main subject: Benzopyrenes / DNA Language: En Journal: J Pharm Sci Year: 1983 Document type: Article

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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Benzopyrenes / DNA Language: En Journal: J Pharm Sci Year: 1983 Document type: Article