Gene expression for interleukin-2 and tumor necrosis factor-alpha in the spleen of old rats under physiological condition and during septic shock. Possible pharmacological modulation.

Annoni, G; Arosio, B; Santambrogio, D; Cullurà, D; Gagliano, N; Uslenghi, C

Annoni, G; Arosio, B; Santambrogio, D; Cullurà, D; Gagliano, N; Uslenghi, C.

Affiliation

Annoni G; Institute of Internal Medicine, University of Milan, Italy.

Arzneimittelforschung ; 44(12A): 1433-6, 1994 Dec.

Article in En | MEDLINE | ID: mdl-7531977

Subject(s)

Gene Expression Regulation/drug effects; Immunologic Factors/pharmacology; Interleukin-2/biosynthesis; Pyrrolidonecarboxylic Acid/analogs & derivatives; Shock, Septic/immunology; Spleen/metabolism; Thiazoles/pharmacology; Tumor Necrosis Factor-alpha/biosynthesis; Aging/immunology; Animals; Blotting, Northern; Interleukin-2/genetics; Male; Pyrrolidonecarboxylic Acid/pharmacology; RNA/biosynthesis; RNA/isolation & purification; Rats; Rats, Sprague-Dawley; Spleen/drug effects; Thiazolidines; Tumor Necrosis Factor-alpha/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidonecarboxylic Acid / Shock, Septic / Spleen / Thiazoles / Gene Expression Regulation / Interleukin-2 / Tumor Necrosis Factor-alpha / Immunologic Factors Limits: Animals Language: En Journal: Arzneimittelforschung Year: 1994 Document type: Article

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