Dexamethasone and suramin inhibit cell proliferation and interleukin-6-mediated immunoglobulin secretion in human lymphoid and multiple myeloma cell lines.

Shiao, R T; Miglietta, L; Khera, S Y; Wolfson, A; Freter, C E

Shiao, R T; Miglietta, L; Khera, S Y; Wolfson, A; Freter, C E.

Affiliation

Shiao RT; Division of Medical Oncology, Vincent T. Lombardi Cancer Research Center, Georgetown University Medical Center, Washington, DC 20007, USA.

Leuk Lymphoma ; 17(5-6): 485-94, 1995 May.

Article in En | MEDLINE | ID: mdl-7549842

Subject(s)

Dexamethasone/pharmacology; Immunoglobulins/biosynthesis; Interleukin-6/antagonists & inhibitors; Lymphocytes/metabolism; Multiple Myeloma/drug therapy; Suramin/pharmacology; Antigens, CD/metabolism; Apoptosis; B-Lymphocytes/metabolism; Cell Division/drug effects; DNA/metabolism; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Immunoglobulins/immunology; Interleukin-6/immunology; Interleukin-6/metabolism; Interleukin-6/pharmacology; Receptors, Interleukin/metabolism; Receptors, Interleukin-6; Time Factors; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Suramin / Immunoglobulins / Dexamethasone / Lymphocytes / Interleukin-6 / Multiple Myeloma Limits: Humans Language: En Journal: Leuk Lymphoma Year: 1995 Document type: Article

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