Down syndrome-critical region contains a gene homologous to Drosophila sim expressed during rat and human central nervous system development.

Dahmane, N; Charron, G; Lopes, C; Yaspo, M L; Maunoury, C; Decorte, L; Sinet, P M; Bloch, B; Delabar, J M

Dahmane, N; Charron, G; Lopes, C; Yaspo, M L; Maunoury, C; Decorte, L; Sinet, P M; Bloch, B; Delabar, J M.

Affiliation

Dahmane N; Unité de Recherche Associée 1335 Centre National de la Recherche Scientifique, Hôpital Necker, Paris, France.

Proc Natl Acad Sci U S A ; 92(20): 9191-5, 1995 Sep 26.

Article in En | MEDLINE | ID: mdl-7568099

Subject(s)

Central Nervous System/embryology; DNA-Binding Proteins/genetics; Down Syndrome/genetics; Drosophila/genetics; Gene Expression; Genes, Insect; Genes, Regulator; Nuclear Proteins/genetics; Amino Acid Sequence; Animals; Base Sequence; Basic Helix-Loop-Helix Transcription Factors; Chromosomes, Human, Pair 21; Cosmids; DNA-Binding Proteins/biosynthesis; Drosophila/embryology; Drosophila Proteins; Embryonic and Fetal Development; Exons; Genome, Human; Helix-Loop-Helix Motifs; Humans; In Situ Hybridization, Fluorescence; Kidney/embryology; Kidney/metabolism; Molecular Sequence Data; Nuclear Proteins/biosynthesis; Oligonucleotide Probes; Organ Specificity; RNA, Messenger/analysis; RNA, Messenger/biosynthesis; Rats; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Sequence Tagged Sites

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Gene Expression / Central Nervous System / Genes, Regulator / Genes, Insect / Down Syndrome / DNA-Binding Proteins / Drosophila Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 1995 Document type: Article

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