A key enzyme in the biosynthesis of neurosteroids, 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase (3 beta-HSD), is expressed in rat brain.

Guennoun, R; Fiddes, R J; Gouézou, M; Lombès, M; Baulieu, E E

Guennoun, R; Fiddes, R J; Gouézou, M; Lombès, M; Baulieu, E E.

Affiliation

Guennoun R; INSERM U33, Lab Hormones, Bicètre, France.

Brain Res Mol Brain Res ; 30(2): 287-300, 1995 Jun.

Article in En | MEDLINE | ID: mdl-7637579

Subject(s)

3-Hydroxysteroid Dehydrogenases/biosynthesis; Brain/metabolism; 3-Hydroxysteroid Dehydrogenases/genetics; Adrenal Glands/metabolism; Animals; Antibodies/immunology; Blotting, Northern; Brain/enzymology; Endocrine Glands/metabolism; Female; Gene Expression; Gonads/metabolism; In Situ Hybridization; Isomerases/biosynthesis; Male; Progesterone/pharmacology; Rats; Rats, Wistar; Steroids/biosynthesis

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Collection: 01-internacional Database: MEDLINE Main subject: Brain / 3-Hydroxysteroid Dehydrogenases Limits: Animals Language: En Journal: Brain Res Mol Brain Res Year: 1995 Document type: Article

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