Evidence for free radical generation due to NADH oxidation by aldehyde oxidase during ethanol metabolism.

Mira, L; Maia, L; Barreira, L; Manso, C F

Mira, L; Maia, L; Barreira, L; Manso, C F.

Affiliation

Mira L; Instituto de Química Fisiológica, Faculdade de Medicina de Lisboa, Portugal.

Arch Biochem Biophys ; 318(1): 53-8, 1995 Apr 01.

Article in En | MEDLINE | ID: mdl-7726572

Subject(s)

Aldehyde Oxidoreductases/metabolism; Ethanol/metabolism; NAD/metabolism; Acetaldehyde/metabolism; Aldehyde Oxidase; Animals; Antioxidants/pharmacology; Ethanol/toxicity; Free Radicals/metabolism; In Vitro Techniques; Kinetics; Lipid Peroxidation/drug effects; Liver/drug effects; Liver/enzymology; Liver/injuries; Male; Microsomes, Liver/metabolism; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Superoxides/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Ethanol / Aldehyde Oxidoreductases / NAD Limits: Animals Language: En Journal: Arch Biochem Biophys Year: 1995 Document type: Article

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