Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response.

Swihart, K; Fruth, U; Messmer, N; Hug, K; Behin, R; Huang, S; Del Giudice, G; Aguet, M; Louis, J A

Swihart, K; Fruth, U; Messmer, N; Hug, K; Behin, R; Huang, S; Del Giudice, G; Aguet, M; Louis, J A.

Affiliation

Swihart K; World Health Organization Immunology Research and Training Center, University of Lausanne, Epalinges, Switzerland.

J Exp Med ; 181(3): 961-71, 1995 Mar 01.

Article in En | MEDLINE | ID: mdl-7869054

Subject(s)

Interferon-gamma/physiology; Leishmania major; Leishmaniasis, Cutaneous/immunology; Receptors, Interferon/physiology; Th1 Cells/immunology; Animals; Antibodies, Monoclonal/immunology; Female; Interleukin-12/physiology; Interleukin-4/physiology; Leishmaniasis, Cutaneous/genetics; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon-gamma / Leishmaniasis, Cutaneous / Receptors, Interferon / Leishmania major / Th1 Cells Limits: Animals Language: En Journal: J Exp Med Year: 1995 Document type: Article

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