[Biologic dosage: its use in high irradiation]. / Dosimetria biologica: l'impiego nelle irradiazioni elevate.

ABSTRACT

It is impossible, in high-dose irradiation, using only one physical dosimeter, to get any valid information to quantify biological damage to subjects, even if it's possible to measure skin-dose with great accuracy. Radiosensibility changes from one subject to another, thus it's necessary to consider some specific biological parameters to evaluate physical conditions of treated patients. Hematological, genetic and chemical tests are valid means to determine the internally distributed dose and to choose the most appropriate therapeutic "protocol".