Ganciclovir treatment of herpes simplex thymidine kinase-transduced primary T lymphocytes: an approach for specific in vivo donor T-cell depletion after bone marrow transplantation?

Tiberghien, P; Reynolds, C W; Keller, J; Spence, S; Deschaseaux, M; Certoux, J M; Contassot, E; Murphy, W J; Lyons, R; Chiang, Y

Tiberghien, P; Reynolds, C W; Keller, J; Spence, S; Deschaseaux, M; Certoux, J M; Contassot, E; Murphy, W J; Lyons, R; Chiang, Y.

Affiliation

Tiberghien P; Biological Carcinogenesis Development Program, Program Resources, Inc, Frederick, MD.

Blood ; 84(4): 1333-41, 1994 Aug 15.

Article in En | MEDLINE | ID: mdl-8049449

Subject(s)

Bone Marrow/immunology; Ganciclovir/pharmacology; Lymphocyte Depletion/methods; Simplexvirus/enzymology; T-Lymphocytes/cytology; T-Lymphocytes/immunology; Thymidine Kinase/biosynthesis; Cell Division/drug effects; Cells, Cultured; Dose-Response Relationship, Drug; Gentamicins/pharmacology; Humans; Interleukin-2/pharmacology; Kinetics; Lymphocyte Activation/drug effects; T-Lymphocytes/drug effects; Time Factors; Transduction, Genetic; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Thymidine Kinase / Bone Marrow / T-Lymphocytes / Ganciclovir / Lymphocyte Depletion / Simplexvirus Limits: Humans Language: En Journal: Blood Year: 1994 Document type: Article

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