Aromatase inhibitors: synthesis, biological activity, and binding mode of azole-type compounds.

Furet, P; Batzl, C; Bhatnagar, A; Francotte, E; Rihs, G; Lang, M

Furet, P; Batzl, C; Bhatnagar, A; Francotte, E; Rihs, G; Lang, M.

Affiliation

Furet P; Research Department, CIBA-GEIGY Ltd, Basle, Switzerland.

J Med Chem ; 36(10): 1393-400, 1993 May 14.

Article in En | MEDLINE | ID: mdl-8496907

Subject(s)

Aromatase Inhibitors; Azoles/chemical synthesis; Estrenes/chemical synthesis; Fadrozole/analogs & derivatives; Azoles/metabolism; Azoles/pharmacology; Binding Sites; Chromatography, High Pressure Liquid; Crystallography; Estrenes/metabolism; Estrenes/pharmacology; Female; Humans; Models, Molecular; Placenta/drug effects; Placenta/enzymology; Stereoisomerism; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Azoles / Fadrozole / Aromatase Inhibitors / Estrenes Limits: Female / Humans Language: En Journal: J Med Chem Year: 1993 Document type: Article

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