[Fertility after treatment for testicular tumor].
Nihon Hinyokika Gakkai Zasshi
; 84(3): 485-9, 1993 Mar.
Article
in Ja
| MEDLINE
| ID: mdl-8515636
ABSTRACT
Thirty-four patients with stage 1 or stage 2A testicular tumor all survived 5 years after the treatment, whereas eighteen patients with stage 2B or 3 testicular tumor, including only nonseminomatous tumor, had a 5-year survival rate of less than 50%. Spermatogenesis returned to normal in 3 patients surviving 22 months after chemotherapy. Five patients who had undergone retroperitoneal lymph node dissection with division of the inferior mesenteric artery developed impaired ejaculation, whereas 3 patients who had undergone the operation without division of the inferior mesenteric artery had normal ejaculation. In 17 patients with right testicular tumor metastases were found in the para-aortic, paracaval and interaortocaval lymph nodes. On the other hand, in 4 patients with left testicular tumor metastases were limited to the para-aortic nodes. These results indicate that impaired spermatogenesis by conventional chemotherapy is reversible in patients with stage 1 or 2 testicular tumor, and patients with stage 1 tumor or stage 2 tumor with localized para-aortic metastases, not involving the inferior mesenteric artery, should undergo retroperitoneal lymph node dissection without division of the inferior mesenteric artery to preserve postoperative fertility.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Testicular Neoplasms
/
Dysgerminoma
/
Fertility
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Humans
/
Infant
/
Male
/
Middle aged
Language:
Ja
Journal:
Nihon Hinyokika Gakkai Zasshi
Year:
1993
Document type:
Article