Application of [125I] (S)-5-iodonicotine, a new radioiodinated ligand, in the assay of nicotinic acetylcholine receptor binding in the brain.

Saji, H; Watanabe, A; Kiyono, Y; Magata, Y; Iida, Y; Takaishi, Y; Yokoyama, A

Saji, H; Watanabe, A; Kiyono, Y; Magata, Y; Iida, Y; Takaishi, Y; Yokoyama, A.

Affiliation

Saji H; Department of Radiopharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Kyoto University, Japan.

Biol Pharm Bull ; 18(11): 1463-6, 1995 Nov.

Article in En | MEDLINE | ID: mdl-8593459

Subject(s)

Brain/metabolism; Nicotine/analogs & derivatives; Receptors, Nicotinic/metabolism; Alkaloids/metabolism; Animals; Azocines; Binding, Competitive; Brain/drug effects; Cerebral Cortex/drug effects; Cerebral Cortex/metabolism; In Vitro Techniques; Iodine Radioisotopes; Isotope Labeling; Kinetics; Ligands; Male; Membranes/drug effects; Membranes/metabolism; Nicotine/metabolism; Nicotine/pharmacology; Quinolizines; Rats; Rats, Wistar; Receptors, Nicotinic/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Brain / Receptors, Nicotinic / Nicotine Limits: Animals Language: En Journal: Biol Pharm Bull Year: 1995 Document type: Article

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