Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response.

Quelle, F W; Wang, D; Nosaka, T; Thierfelder, W E; Stravopodis, D; Weinstein, Y; Ihle, J N

Quelle, F W; Wang, D; Nosaka, T; Thierfelder, W E; Stravopodis, D; Weinstein, Y; Ihle, J N.

Affiliation

Quelle FW; Department of Biochemistry, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

Mol Cell Biol ; 16(4): 1622-31, 1996 Apr.

Article in En | MEDLINE | ID: mdl-8657137

Subject(s)

Cell Division/genetics; DNA-Binding Proteins/metabolism; Erythropoietin/pharmacology; Milk Proteins; Proto-Oncogene Proteins; Receptors, Erythropoietin/metabolism; Trans-Activators/metabolism; Tyrosine/metabolism; Amino Acid Sequence; Animals; Cell Division/drug effects; Cell Line; DNA-Binding Proteins/genetics; Enzyme Activation; Humans; Janus Kinase 2; Molecular Sequence Data; Mutation; Protein-Tyrosine Kinases/genetics; Protein-Tyrosine Kinases/metabolism; Receptors, Antigen, T-Cell, gamma-delta/drug effects; Receptors, Antigen, T-Cell, gamma-delta/genetics; Receptors, Antigen, T-Cell, gamma-delta/metabolism; Receptors, Erythropoietin/drug effects; Receptors, Erythropoietin/genetics; STAT5 Transcription Factor; Trans-Activators/genetics; Tumor Suppressor Proteins

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tyrosine / Trans-Activators / Cell Division / Proto-Oncogene Proteins / Erythropoietin / Receptors, Erythropoietin / DNA-Binding Proteins / Milk Proteins Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: Mol Cell Biol Year: 1996 Document type: Article

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