Panencephalitic Creutzfeldt-Jakob disease. Unusual presentation of magnetic resonance imaging and proton magnetic resonance spectroscopy.
J Neurol Sci
; 138(1-2): 157-60, 1996 Jun.
Article
in En
| MEDLINE
| ID: mdl-8791254
ABSTRACT
We present serial magnetic resonance imaging (MRI) scans on a biopsy-verified case of Creutzfeldt-Jakob disease (CJD). The initial MRI scan demonstrated increased T2 signal-intensity within the basal ganglia and thalami. Subsequent MRI scans demonstrated a thin cortex, increased T2 signals diffusely within the white matter including U-fibers, and hypointense T2 signals within the basal ganglia, and thalami. Proton magnetic resonance spectroscopy (1H-MRS) study showed an absence of creatine, choline and N-acetylaspartate signals. By these characteristic findings, serial MRI and MRS studies may be helpful in differentiating CJD from other dementing illnesses.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Brain
/
Magnetic Resonance Imaging
/
Magnetic Resonance Spectroscopy
/
Cerebral Cortex
/
Creutzfeldt-Jakob Syndrome
Limits:
Female
/
Humans
/
Middle aged
Language:
En
Journal:
J Neurol Sci
Year:
1996
Document type:
Article