International, collaborative experience of 1789 patients having multifetal pregnancy reduction: a plateauing of risks and outcomes.
J Soc Gynecol Investig
; 3(1): 23-6, 1996.
Article
in En
| MEDLINE
| ID: mdl-8796803
ABSTRACT
OBJECTIVE:
To develop the most up-to-date, complete data base of multifetal pregnancy reduction (MFPR) from cases, and to provide the best counseling for couples with multifetal pregnancies.METHODS:
From nine centers in five countries, 1789 completed MFPR cases were collected and outcomes evaluated. Pregnancy losses were defined as through 24 weeks and deliveries categorized in groups of 25-28, 29-32, 33-36, and 37 or more weeks.RESULTS:
Overall, the pregnancy loss rate was 11.7% but varied from a low of 7.6% for triplets to twins and increased with each additional starting number to 22.9% for sextuplets or higher. Early premature deliveries (25-28 weeks) were 4.5% and varied with starting number. Loss rates by finishing number were highest for triplets and lowest for twins, but gestational age at delivery was highest for singletons.CONCLUSIONS:
Multifetal pregnancy reduction has been shown to be a safe and effective method to improve outcome in multifetal pregnancies. Outcomes are worse with higher-order gestations and support the need for continued vigilance of fertility therapy.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Infant, Premature
/
Abortion, Spontaneous
/
Pregnancy Reduction, Multifetal
Type of study:
Clinical_trials
/
Etiology_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Newborn
/
Pregnancy
Language:
En
Journal:
J Soc Gynecol Investig
Year:
1996
Document type:
Article