In vivo and in vitro interaction of flunarizine with D-fenfluramine serotonergic effects.

Mennini, T; Gobbi, M; Crespi, D; Cinquanta, M; Frittoli, E; Giorcelli, P; Anelli, M; Caccia, S

Mennini, T; Gobbi, M; Crespi, D; Cinquanta, M; Frittoli, E; Giorcelli, P; Anelli, M; Caccia, S.

Affiliation

Mennini T; Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy.

Pharmacol Biochem Behav ; 53(1): 155-61, 1996 Jan.

Article in En | MEDLINE | ID: mdl-8848445

Subject(s)

Fenfluramine/antagonists & inhibitors; Fenfluramine/pharmacology; Flunarizine/pharmacology; Selective Serotonin Reuptake Inhibitors/pharmacology; Serotonin/physiology; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases/metabolism; Cerebral Cortex/drug effects; Cerebral Cortex/enzymology; Cerebral Cortex/metabolism; Dopamine/metabolism; Drug Interactions; Hydroxyindoleacetic Acid/metabolism; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Serotonin/metabolism; Synaptosomes/drug effects; Synaptosomes/enzymology; Synaptosomes/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Flunarizine / Serotonin / Selective Serotonin Reuptake Inhibitors / Fenfluramine Limits: Animals Language: En Journal: Pharmacol Biochem Behav Year: 1996 Document type: Article

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