Effects of doxylamine succinate on thyroid hormone balance and enzyme induction in mice.

Bookstaff, R C; Murphy, V A; Skare, J A; Minnema, D; Sanzgiri, U; Parkinson, A

Bookstaff, R C; Murphy, V A; Skare, J A; Minnema, D; Sanzgiri, U; Parkinson, A.

Affiliation

Bookstaff RC; The Procter & Gamble Company, Cincinnati, Ohio 45040-9462, USA.

Toxicol Appl Pharmacol ; 141(2): 584-94, 1996 Dec.

Article in En | MEDLINE | ID: mdl-8975784

Subject(s)

Cytochrome P-450 Enzyme System/biosynthesis; Doxylamine/analogs & derivatives; Histamine H1 Antagonists/toxicity; Thyroid Hormones/blood; Animals; Doxylamine/toxicity; Enzyme Induction/drug effects; Female; Hydroxylation; Lauric Acids/metabolism; Male; Mice; Microsomes, Liver/drug effects; Microsomes, Liver/enzymology; Phenobarbital/pharmacology; Testosterone/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Thyroid Hormones / Cytochrome P-450 Enzyme System / Doxylamine / Histamine H1 Antagonists Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 1996 Document type: Article

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