Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.

Ellis, J; Pasceri, P; Tan-Un, K C; Wu, X; Harper, A; Fraser, P; Grosveld, F

Ellis, J; Pasceri, P; Tan-Un, K C; Wu, X; Harper, A; Fraser, P; Grosveld, F.

Affiliation

Ellis J; Department of Genetics, Blood Gene Therapy Program and Program in Developmental Biology, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G1X8, Canada. jellis@sickkids.on.ca

Nucleic Acids Res ; 25(6): 1296-302, 1997 Mar 15.

Article in En | MEDLINE | ID: mdl-9092642

Subject(s)

Genetic Therapy; Globins/genetics; Mice, Transgenic; Animals; DNA Primers; DNA Transposable Elements; Dimerization; Fetus; Gene Expression; Globins/biosynthesis; Humans; Liver/metabolism; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred Strains; Polymerase Chain Reaction; Promoter Regions, Genetic; Reproducibility of Results

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Globins / Mice, Transgenic / Genetic Therapy Limits: Animals / Humans Language: En Journal: Nucleic Acids Res Year: 1997 Document type: Article

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