Determination of a substance P antagonist in human plasma and urine using high-performance liquid chromatography with ultraviolet absorbance and tandem mass spectrometric detection.

Zagrobelny, J; Chavez, C; Constanzer, M L; Matuszewski, B K

Zagrobelny, J; Chavez, C; Constanzer, M L; Matuszewski, B K.

Affiliation

Zagrobelny J; Department of Drug Metabolism, Merck Research Laboratories, West Point, PA 19486, USA.

J Pharm Biomed Anal ; 15(9-10): 1427-33, 1997 Jun.

Article in En | MEDLINE | ID: mdl-9226572

Subject(s)

Chromatography, High Pressure Liquid/methods; Mass Spectrometry/methods; Morpholines/analysis; Substance P/antagonists & inhibitors; Humans; Morpholines/blood; Morpholines/urine; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

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Collection: 01-internacional Database: MEDLINE Main subject: Mass Spectrometry / Substance P / Morpholines / Chromatography, High Pressure Liquid Type of study: Diagnostic_studies Limits: Humans Language: En Journal: J Pharm Biomed Anal Year: 1997 Document type: Article

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