Yeast hexokinase inhibitors designed from the 3-D enzyme structure rebuilding.

Willson, M; Alric, I; Perie, J; Sanejouand, Y H

Willson, M; Alric, I; Perie, J; Sanejouand, Y H.

Affiliation

Willson M; Groupe de Chimie Organique Biologique, IMRCP UMR-CNRS 5623, Université Paul Sabatier, Toulouse, France. willson@iris.ups-tlse.fr

J Enzyme Inhib ; 12(2): 101-21, 1997 Jun.

Article in En | MEDLINE | ID: mdl-9247853

Subject(s)

Enzyme Inhibitors/chemical synthesis; Glucosamine/pharmacology; Hexokinase/antagonists & inhibitors; Amino Acid Sequence; Crystallography, X-Ray; Drug Design; Glucosamine/analogs & derivatives; Hydrogen Bonding; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Sequence Data; Protein Conformation; Saccharomyces cerevisiae; Sequence Alignment

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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Enzyme Inhibitors / Glucosamine / Hexokinase Language: En Journal: J Enzyme Inhib Year: 1997 Document type: Article

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