Mapping the active site of factor Xa by selective inhibitors: an NMR and MD study.

Fraternali, F; Do, Q T; Doan, B T; Atkinson, R A; Palmas, P; Sklenar, V; Safar, P; Wildgoose, P; Strop, P; Saudek, V

Fraternali, F; Do, Q T; Doan, B T; Atkinson, R A; Palmas, P; Sklenar, V; Safar, P; Wildgoose, P; Strop, P; Saudek, V.

Affiliation

Fraternali F; Marion Merrell Research Institute, HMR, Strasbourg, France.

Proteins ; 30(3): 264-74, 1998 Feb 15.

Article in En | MEDLINE | ID: mdl-9517542

Subject(s)

Factor Xa/chemistry; Amino Acid Sequence; Binding Sites/physiology; Enzyme Inhibitors/chemistry; Enzyme Inhibitors/pharmacology; Factor Xa Inhibitors; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Peptide Library; Peptides/chemistry; Peptides/pharmacology; Protein Structure, Tertiary; Sequence Alignment

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Collection: 01-internacional Database: MEDLINE Main subject: Factor Xa Type of study: Prognostic_studies Limits: Humans Language: En Journal: Proteins Year: 1998 Document type: Article

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