gp41 envelope protein of human immunodeficiency virus induces interleukin (IL)-10 in monocytes, but not in B, T, or NK cells, leading to reduced IL-2 and interferon-gamma production.

Barcova, M; Kacani, L; Speth, C; Dierich, M P

Barcova, M; Kacani, L; Speth, C; Dierich, M P.

Affiliation

Barcova M; Institute for Hygiene, University of Innsbruck and Ludwig-Boltzmann-Institute for AIDS Research, Austria.

J Infect Dis ; 177(4): 905-13, 1998 Apr.

Article in En | MEDLINE | ID: mdl-9534962

Subject(s)

HIV Envelope Protein gp41/immunology; HIV Infections/immunology; HIV-1/immunology; Monocytes/immunology; Monocytes/metabolism; Antibodies, Blocking/immunology; B-Lymphocytes/immunology; B-Lymphocytes/metabolism; Carrier Proteins/genetics; Cells, Cultured; Enterotoxins/immunology; HIV Envelope Protein gp41/genetics; Humans; Interferon-gamma/immunology; Interferon-gamma/metabolism; Interleukin-10/immunology; Interleukin-10/metabolism; Interleukin-2/immunology; Interleukin-2/metabolism; Interleukin-4/immunology; Interleukin-4/metabolism; Killer Cells, Natural/immunology; Killer Cells, Natural/metabolism; Kinetics; Maltose-Binding Proteins; Recombinant Fusion Proteins/immunology; T-Lymphocytes/immunology; T-Lymphocytes/metabolism; Tumor Necrosis Factor-alpha/immunology; Tumor Necrosis Factor-alpha/metabolism

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Collection: 01-internacional Health context: 2_ODS3 Database: MEDLINE Main subject: Monocytes / HIV Envelope Protein gp41 / HIV Infections / HIV-1 Limits: Humans Language: En Journal: J Infect Dis Year: 1998 Document type: Article

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