[A case of Sairei-to-induced pneumonitis diagnosed by lymphocyte stimulation test of bronchoalveolar lavage fluid].
Nihon Kyobu Shikkan Gakkai Zasshi
; 35(12): 1347-51, 1997 Dec.
Article
in Ja
| MEDLINE
| ID: mdl-9567079
ABSTRACT
A 51-year-old woman was admitted with fever, cough and dyspnea. She had been taking Sairei-to, a traditional Chinese medicine, for 2 months. On admission, chest X-ray revealed a ground-glass appearance in the lung fields bilaterally and serum LDH was elevated. A differential cell count of the bronchoalveolar lavage fluid (BALF) showed that lymphocytes were increased, with a decreased ratio of CD4/CD8 cells. A lymphocyte stimulation test (LST) for Sairei-to using the lymphocytes in BALF was a positive, although a test of peripheral blood was negative. Sairei-to-induced pneumonitis was diagnosed based on the clinical course, laboratory findings, BALF cell analysis and LST of BALF. Only 4 cases of pneumonitis due to Sairei-to have been reported. This case suggests that LST of BALF is useful for diagnosing drug-induced pneumonitis.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pneumonia
/
Bronchoalveolar Lavage Fluid
/
Drugs, Chinese Herbal
/
Lymphocyte Activation
Type of study:
Diagnostic_studies
Limits:
Female
/
Humans
/
Middle aged
Language:
Ja
Journal:
Nihon Kyobu Shikkan Gakkai Zasshi
Year:
1997
Document type:
Article