Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant.

Marchetti, M; Rossi, M; Giannelli, V; Giuliani, M M; Pizza, M; Censini, S; Covacci, A; Massari, P; Pagliaccia, C; Manetti, R; Telford, J L; Douce, G; Dougan, G; Rappuoli, R; Ghiara, P

Marchetti, M; Rossi, M; Giannelli, V; Giuliani, M M; Pizza, M; Censini, S; Covacci, A; Massari, P; Pagliaccia, C; Manetti, R; Telford, J L; Douce, G; Dougan, G; Rappuoli, R; Ghiara, P.

Affiliation

Marchetti M; IRIS, Chiron Vaccines Immunobiological Research Institute Siena, Italy.

Vaccine ; 16(1): 33-7, 1998 Jan.

Article in En | MEDLINE | ID: mdl-9607006

Subject(s)

Adjuvants, Immunologic; Antigens, Bacterial/immunology; Bacterial Toxins; Bacterial Vaccines/therapeutic use; Enterotoxins; Escherichia coli Proteins; Helicobacter Infections/prevention & control; Helicobacter pylori/immunology; Animals; Bacterial Vaccines/immunology; Male; Mice; Vaccines, Synthetic/immunology; Vaccines, Synthetic/therapeutic use

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Toxins / Bacterial Vaccines / Adjuvants, Immunologic / Helicobacter pylori / Helicobacter Infections / Escherichia coli Proteins / Enterotoxins / Antigens, Bacterial Limits: Animals Language: En Journal: Vaccine Year: 1998 Document type: Article

Search on Google

XML

PubMed Links