Full activation of MEN2B mutant RET by an additional MEN2A mutation or by ligand GDNF stimulation.

Bongarzone, I; Vigano, E; Alberti, L; Borrello, M G; Pasini, B; Greco, A; Mondellini, P; Smith, D P; Ponder, B A; Romeo, G; Pierotti, M A

Bongarzone, I; Vigano, E; Alberti, L; Borrello, M G; Pasini, B; Greco, A; Mondellini, P; Smith, D P; Ponder, B A; Romeo, G; Pierotti, M A.

Affiliation

Bongarzone I; Division of Experimental Oncology A, Istituto Nazionale Tumori, Milan, Italy.

Oncogene ; 16(18): 2295-301, 1998 May 07.

Article in En | MEDLINE | ID: mdl-9620546

Subject(s)

Drosophila Proteins; Multiple Endocrine Neoplasia Type 2a/genetics; Multiple Endocrine Neoplasia Type 2b/genetics; Mutation; Nerve Tissue Proteins/pharmacology; Proto-Oncogene Proteins/genetics; Receptor Protein-Tyrosine Kinases/genetics; 3T3 Cells; Animals; Dimerization; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Humans; Ligands; Mice; Nerve Growth Factors/pharmacology; Proto-Oncogene Proteins c-ret; Recombinant Proteins; Transfection

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins / Receptor Protein-Tyrosine Kinases / Multiple Endocrine Neoplasia Type 2b / Multiple Endocrine Neoplasia Type 2a / Drosophila Proteins / Mutation / Nerve Tissue Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Oncogene Year: 1998 Document type: Article

Search on Google

XML

PubMed Links