Sustained release of injectable zinc-recombinant hirudin suspensions: development and validation of in vitro release model.

Gietz, U; Arvinte, T; Mader, E; Oroszlan, P; Merkle, H P

Gietz, U; Arvinte, T; Mader, E; Oroszlan, P; Merkle, H P.

Affiliation

Gietz U; Swiss Federal Institute of Technology Zürich (ETH), Switzerland.

Eur J Pharm Biopharm ; 45(3): 259-64, 1998 May.

Article in En | MEDLINE | ID: mdl-9653630

Subject(s)

Anticoagulants/pharmacokinetics; Hirudins/pharmacokinetics; Algorithms; Anticoagulants/administration & dosage; Buffers; Delayed-Action Preparations; Fiber Optic Technology; Hirudins/administration & dosage; Humans; Insulin/administration & dosage; Insulin/pharmacokinetics; Models, Biological; Recombinant Proteins/administration & dosage; Recombinant Proteins/pharmacokinetics; Suspensions

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Collection: 01-internacional Database: MEDLINE Main subject: Hirudins / Anticoagulants Limits: Humans Language: En Journal: Eur J Pharm Biopharm Year: 1998 Document type: Article

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