Antitumor activity of DAB389IL-2 fusion toxin in mycosis fungoides.

Saleh, M N; LeMaistre, C F; Kuzel, T M; Foss, F; Platanias, L C; Schwartz, G; Ratain, M; Rook, A; Freytes, C O; Craig, F; Reuben, J; Sams, M W; Nichols, J C

Saleh, M N; LeMaistre, C F; Kuzel, T M; Foss, F; Platanias, L C; Schwartz, G; Ratain, M; Rook, A; Freytes, C O; Craig, F; Reuben, J; Sams, M W; Nichols, J C.

Affiliation

Saleh MN; The University of Alabama at Birmingham, USA.

J Am Acad Dermatol ; 39(1): 63-73, 1998 Jul.

Article in En | MEDLINE | ID: mdl-9674399

Subject(s)

Antineoplastic Agents/therapeutic use; Diphtheria Toxin/therapeutic use; Immunosuppressive Agents/therapeutic use; Immunotoxins/therapeutic use; Interleukin-2/therapeutic use; Mycosis Fungoides/therapy; Recombinant Fusion Proteins/therapeutic use; Skin Neoplasms/therapy; Adult; Aged; Aged, 80 and over; Antineoplastic Agents/administration & dosage; Antineoplastic Agents/adverse effects; Dermatitis, Exfoliative/therapy; Diphtheria Toxin/administration & dosage; Diphtheria Toxin/adverse effects; Female; Fever/etiology; Humans; Hypotension/etiology; Immunosuppressive Agents/administration & dosage; Immunosuppressive Agents/adverse effects; Immunotoxins/administration & dosage; Immunotoxins/adverse effects; Infusions, Intravenous; Interleukin-2/administration & dosage; Interleukin-2/adverse effects; Lymphoma, T-Cell, Cutaneous/therapy; Male; Middle Aged; Mycosis Fungoides/pathology; Nausea/etiology; Neoplasm Staging; Receptors, Interleukin-2/antagonists & inhibitors; Recombinant Fusion Proteins/administration & dosage; Recombinant Fusion Proteins/adverse effects; Remission Induction; Shivering/physiology; Skin Neoplasms/pathology; Vomiting/etiology

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Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Recombinant Fusion Proteins / Immunotoxins / Mycosis Fungoides / Interleukin-2 / Diphtheria Toxin / Immunosuppressive Agents / Antineoplastic Agents Type of study: Clinical_trials / Etiology_studies Limits: Aged80 Language: En Journal: J Am Acad Dermatol Year: 1998 Document type: Article

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