The three-dimensional structure of a class-Pi glutathione S-transferase complexed with glutathione: the active-site hydration provides insights into the reaction mechanism.

Párraga, A; García-Sáez, I; Walsh, S B; Mantle, T J; Coll, M

Párraga, A; García-Sáez, I; Walsh, S B; Mantle, T J; Coll, M.

Affiliation

Párraga A; Departament de Biologia Molecular i Cel.lular, Centre d'Investigació i Desenvolupament-CSIC, Jordi Girona 18-26, 08034 Barcelona, Spain.

Biochem J ; 333 ( Pt 3): 811-6, 1998 Aug 01.

Article in En | MEDLINE | ID: mdl-9677344

Subject(s)

Glutathione Transferase/chemistry; Glutathione Transferase/metabolism; Glutathione/chemistry; Glutathione/metabolism; Animals; Binding Sites; Crystallography, X-Ray; Enzyme Activation; Liver/enzymology; Mice; Molecular Conformation; Protein Conformation; Protein Structure, Secondary; Water/chemistry; Water/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glutathione / Glutathione Transferase Limits: Animals Language: En Journal: Biochem J Year: 1998 Document type: Article

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