Transcriptional activating activity of Smad4: roles of SMAD hetero-oligomerization and enhancement by an associating transactivator.

Shioda, T; Lechleider, R J; Dunwoodie, S L; Li, H; Yahata, T; de Caestecker, M P; Fenner, M H; Roberts, A B; Isselbacher, K J

Shioda, T; Lechleider, R J; Dunwoodie, S L; Li, H; Yahata, T; de Caestecker, M P; Fenner, M H; Roberts, A B; Isselbacher, K J.

Affiliation

Shioda T; Laboratory of Tumor Biology, Massachusetts General Hospital Cancer Center, Massachusetts General Hospital-East, Charlestown, MA 02129-2060, USA. shioda@helix.mgh.harvard.edu

Proc Natl Acad Sci U S A ; 95(17): 9785-90, 1998 Aug 18.

Article in En | MEDLINE | ID: mdl-9707553

Subject(s)

DNA-Binding Proteins; Saccharomyces cerevisiae Proteins; Trans-Activators/metabolism; 3T3 Cells; Animals; Apoptosis Regulatory Proteins; Binding Sites; Humans; In Vitro Techniques; Mice; Mutation; Nuclear Proteins/chemistry; Nuclear Proteins/genetics; Nuclear Proteins/metabolism; Protein Conformation; Recombinant Fusion Proteins/chemistry; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/metabolism; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/metabolism; Signal Transduction; Smad4 Protein; Trans-Activators/chemistry; Trans-Activators/genetics; Transcription Factors/chemistry; Transcription Factors/genetics; Transcription Factors/metabolism; Transcriptional Activation; Transfection; Transforming Growth Factor beta/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trans-Activators / Saccharomyces cerevisiae Proteins / DNA-Binding Proteins Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 1998 Document type: Article

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