Electrophysiological evidence that noradrenergic neurons of the rat locus coeruleus are tonically inhibited by GABA during sleep.

Gervasoni, D; Darracq, L; Fort, P; Soulière, F; Chouvet, G; Luppi, P H

Gervasoni, D; Darracq, L; Fort, P; Soulière, F; Chouvet, G; Luppi, P H.

Affiliation

Gervasoni D; Laboratoire de Médecine Expérimentale, INSERM U480, CNRS ERS 5645, Faculté de Pharmacie, Université Claude Bernard Lyon I, France. gervasoni@sommeil.univ-lyon1.fr

Eur J Neurosci ; 10(3): 964-70, 1998 Mar.

Article in En | MEDLINE | ID: mdl-9753163

Subject(s)

Locus Coeruleus/physiology; Neurons/physiology; Norepinephrine/physiology; Sleep/physiology; gamma-Aminobutyric Acid/pharmacology; Animals; Bicuculline/administration & dosage; Bicuculline/pharmacology; Electrophysiology; GABA Antagonists/administration & dosage; GABA Antagonists/pharmacology; Iontophoresis; Locus Coeruleus/cytology; Locus Coeruleus/drug effects; Male; Neurons/drug effects; Polysomnography/drug effects; Rats; Rats, Sprague-Dawley; Restraint, Physical; Wakefulness/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Sleep / Locus Coeruleus / Norepinephrine / Gamma-Aminobutyric Acid / Neurons Limits: Animals Language: En Journal: Eur J Neurosci Year: 1998 Document type: Article

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