Adhesion-dependent degranulation of neutrophils requires the Src family kinases Fgr and Hck.

Mócsai, A; Ligeti, E; Lowell, C A; Berton, G

Mócsai, A; Ligeti, E; Lowell, C A; Berton, G.

Affiliation

Mócsai A; Institute of General Pathology, University of Verona, Italy.

J Immunol ; 162(2): 1120-6, 1999 Jan 15.

Article in En | MEDLINE | ID: mdl-9916742

Subject(s)

Cell Degranulation/physiology; Neutrophils/enzymology; Neutrophils/physiology; Protein-Tyrosine Kinases/physiology; Proto-Oncogene Proteins/physiology; src-Family Kinases/physiology; Animals; Cell Adhesion/drug effects; Cell Adhesion/genetics; Cell Adhesion/physiology; Cell Degranulation/drug effects; Cell Degranulation/genetics; Enzyme Inhibitors/pharmacology; Female; Humans; Lactoferrin/antagonists & inhibitors; Lactoferrin/genetics; Lactoferrin/metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils/metabolism; Protein-Tyrosine Kinases/antagonists & inhibitors; Protein-Tyrosine Kinases/genetics; Proto-Oncogene Proteins/antagonists & inhibitors; Proto-Oncogene Proteins/genetics; Proto-Oncogene Proteins c-hck; Pyrazoles/pharmacology; Pyrimidines/pharmacology; Tumor Necrosis Factor-alpha/pharmacology; src-Family Kinases/antagonists & inhibitors; src-Family Kinases/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Protein-Tyrosine Kinases / Cell Degranulation / Proto-Oncogene Proteins / Src-Family Kinases / Neutrophils Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: J Immunol Year: 1999 Document type: Article

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