Comparison of the nasopharynx microbiome between influenza and noninfluenza cases of severe acute respiratory infections: a pilot study
Health Sci Rep
; 1(6): 1-7, June 2018. tab
Artigo
em Inglês
| Coleciona SUS, CONASS, SES-RS
| ID: biblio-1120552
Biblioteca responsável:
BR1618.1
ABSTRACT
Aims:
Influenza A virus (IAV) can cause severe acute respiratory infection (SARI), and disease outcome may be associated with changes in the microbiome of the nasopharynx. This is a pilot study to characterize the microbiome of the nasopharynx in patients hospitalized with SARI, infected and not infected by IAV. Methods andResults:
Using target sequencing of the 16S rRNA gene, we assessed the bacterial community of nasopharyngeal aspirate samples and compared the microbiome of patients infected with IAV with the microbiome of patients who were negative for IAV. We observed differences in the relative abundance of Proteobacteria and Firmicutes between SARI patients, with Streptococcus being enriched and Pseudomonas underrepresented in IAV patients compared with patients who were not infected with IAV.Conclusion:
Pseudomonas taxon seems to be in high frequency on the nasopharynx of SARI patients with nonIAV infection and might present a negative association with Streptococcus taxon. Microbial profile appears to be different between SARI patients infected or not infected with IAV.
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Brasil
Base de dados:
CONASS
/
SES-RS
/
Coleciona SUS
Assunto principal:
Vírus da Influenza A
/
Doenças Respiratórias
/
Infecções Respiratórias
/
Coinfecção
/
Microbiota
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Health Sci Rep
Ano de publicação:
2018
Tipo de documento:
Artigo
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