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HTLV-2 infection in Manaus, Brazil: first description of HTLV-2c subtype in an urban area of the Western Amazon region

Pontes, Gemilson Soares; Ribeiro, Hygor Halyson Figueiredo; Toro, Diana Mota; Moura Neto, José Pereira de; Souza, Victor; Almeida, Maria Edilene Martins de; Nascimento, Valdinete Alves do; Costa, Cristovão Alves da; Naveca, Felipe Gomes; Santos, Mike; Vallinoto, Antonio Carlos Rosário.
Rev. Soc. Bras. Med. Trop; 54: e20200066, 2021. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-1136919
Abstract

INTRODUCTION:

We investigated the prevalence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) infection in patients with hematological diseases from the western Amazon region of Brazil.

METHODS:

Samples from 306 patients were submitted for the molecular diagnosis of HTLV-1/2 infection by real time PCR (qPCR), with amplification, sequencing, and phylogenetic analysis of the long terminal repeat (LTR) region.

RESULTS:

A 29-year-old male carrier of sickle cell anemia with a history of multiple blood transfusions was diagnosed with the HTLV-2c subtype.

CONCLUSIONS:

This study describes the first known occurrence of HTLV-2c in the urban area of Brazil's western Amazon region.
Biblioteca responsável: BR1.1
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