HTLV-2 infection in Manaus, Brazil: first description of HTLV-2c subtype in an urban area of the Western Amazon region
Pontes, Gemilson Soares; Ribeiro, Hygor Halyson Figueiredo; Toro, Diana Mota; Moura Neto, José Pereira de; Souza, Victor; Almeida, Maria Edilene Martins de; Nascimento, Valdinete Alves do; Costa, Cristovão Alves da; Naveca, Felipe Gomes; Santos, Mike; Vallinoto, Antonio Carlos Rosário.
Rev. Soc. Bras. Med. Trop;
54: e20200066, 2021. tab, graf
Artigo
em Inglês
|
LILACS-Express
| ID: biblio-1136919
Abstract
INTRODUCTION:
We investigated the prevalence of human T-cell lymphotropic virus types 1 and 2 (HTLV-1/2) infection in patients with hematological diseases from the western Amazon region of Brazil.METHODS:
Samples from 306 patients were submitted for the molecular diagnosis of HTLV-1/2 infection by real time PCR (qPCR), with amplification, sequencing, and phylogenetic analysis of the long terminal repeat (LTR) region.RESULTS:
A 29-year-old male carrier of sickle cell anemia with a history of multiple blood transfusions was diagnosed with the HTLV-2c subtype.CONCLUSIONS:
This study describes the first known occurrence of HTLV-2c in the urban area of Brazil's western Amazon region.
Biblioteca responsável:
BR1.1
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