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Molecular epidemiology and drug resistance of Acinetobacter baumannii isolated from a regional hospital in the Brazilian Amazon region

Ribeiro, Edlainny Araujo; Gales, Ana Cristina; Oliveira, Ana Paula Streling de; Coelho, Danilo Dias; Oliveira, Rodrigo Alves de; Pfrimer, Irmtraut Araci Hoffmann; Carmo Filho, José Rodrigues do.
Rev. Soc. Bras. Med. Trop; 54: e20200087, 2021. tab, graf
Artigo em Inglês | LILACS-Express | ID: biblio-1136920
Abstract

INTRODUCTION:

In this study, we report a clonal dissemination of carbapenem resistant Acinetobacter baumannii isolates due to the acquisition of blaOXA-23 in a regional hospital located in Brazilian Amazon Region.

METHODS:

The isolates were identified by MALDI-TOF and the carbapenemase-encoding genes were detected by multiplex-PCR. The genetic similarity was investigated by pulsed-field gel electrophoresis (PFGE).

RESULTS:

Only 10 (55.6%) isolates harbored the gene bla OXA-23. PFGE analysis revealed that these isolates belong to a single clone.

CONCLUSIONS:

This dissemination strategy indicates the need for surveillance, adoption of control procedures defined in guidelines, and the careful administration of antimicrobials should be reinforced.
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