Cellular inactivation induced by H2O2 and active oxygen species generated by environmental stresses in bacteria
Ciênc. cult. (Säo Paulo)
; 48(1/2): 55-63, Jan.-Apr. 1996.
Article
em En
| LILACS
| ID: lil-191243
Biblioteca responsável:
BR1.1
ABSTRACT
Oxyygen free radicals are highly reactive species that damage several cellular macromolecules and organelles, including membrane lipid peroxidation and produce DNA lesions. We have discussed here; i) The mechanism of radiation-induced cellular damage in bacteria through the intermediation of active oxygen species; ii) the cellular inactivation and the role of bacterial SOS and OxyR systems in the repair of lesions induced by H2O2 under low iron condition; iii) the lethal interaction between H2O2 and o-phenanthroline in E. coli; iv) the biological response induced by near-UV radiation mediated by active oxygen species and finally v) the mutagenic potential of popular plant extracts like guaraná (Paullinia cupana), mate (Ilex paraguariensis) and saiao (Kalanchoe brasiliensis), whose effects are eventually mediated by active oxygen species.
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Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
LILACS
Assunto principal:
Bactérias
/
Dano ao DNA
/
Peroxidação de Lipídeos
/
Células
/
Oxidantes
/
Espécies Reativas de Oxigênio
/
Estresse Oxidativo
/
Peróxido de Hidrogênio
Idioma:
En
Revista:
Ciênc. cult. (Säo Paulo)
Ano de publicação:
1996
Tipo de documento:
Article