Genomic and phylogenetic analysis of hapatitis C virus strains from Argentina
Medicina (B.Aires)
; 58(2): 153-9, 1998. tab, graf
Article
em En
| LILACS
| ID: lil-212787
Biblioteca responsável:
BR1.1
ABSTRACT
HCV genomic characterization was performed by nucleotide sequence analysis (n=50) combined with restriction fragment length polymorphism (RFLP) of the 5'UTR region in 82 isolates coresponding to different Argentine groups. Genotype 1 was detected in 70.7 percent of the samples (58 out of 82), genotype 2 in 21.9 percent (18 of 82) and genotypes 3 in the remaining 6 sera (7.3 percent). HCV ib subtype contributed with 35.3 percent to the whole population studied (29 of 82) and was detected in 6 out of 21 sporadic cases. Besides their epidemiological significance, these results should be taken into account when future vaccines are considered on the basis of geographical HCV genotypic prevalence.
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Filogenia
/
Polimorfismo de Fragmento de Restrição
/
Hepacivirus
/
Hepatite C Crônica
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
País/Região como assunto:
America do sul
/
Argentina
Idioma:
En
Revista:
Medicina (B.Aires)
Ano de publicação:
1998
Tipo de documento:
Article