Effect of malnutrition at the time of diagnosis on the survival of children treated for cancer in El Salvador and Northern Brazil
Rev. IMIP
; 14(1): 54-7, jan.-jun. 2000. ilus
Article
em En
| LILACS
| ID: lil-273257
Biblioteca responsável:
BR6.1
ABSTRACT
Purpose:
To investigate the relationship between survival and malnutrition at the time of diagnosis among children treated for cancer in two developing countries. Patients andMethods:
We studied 443 children treated for cancer between 1995 and 1998 at two centers in San Salvador, El Salvador, and Recife, Brazil. Median age at diagnosis was 4.9 years; 283 children had leukemia and 260 had solid tumors. Z scores were calculated for weight for age (WAZ), height for age (HAZ), and weight for height (WHZ) at diagnosis. Z scores < -2 indicated malnutrition. Patients were also stratified by low-risk disease (solid tumors stage I, stage II, or localized; acute lymphocytic leukemia WBC count < 25,000/uL, negative CNS, no mediastinal mass and age > 1 and < 10 years) and high-risk disease (all other patients, including those with acute or chronic myelocytic leukemia).Results:
Z scores indicated malnutrition in 15.7 por cento (WHZ), 23.5 por cento (WAZ), and 22.8 por cento (HAZ) of patients. Z score was not significantly related to overall survival rates, to survival rates analyzed by type of malignancy or risk status, or to survival rates at the end of the first month of treatment.Conclusions:
We found no relationship between nutritional status and survival in these patients. This implies that future protocols for use in developing countries can be designed to provide optimal treatment intensity despite the high incidence of malnutrition
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Neoplasias
/
Distúrbios Nutricionais
Tipo de estudo:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
Limite:
Child
/
Child, preschool
/
Humans
/
Infant
/
Newborn
País/Região como assunto:
America central
/
America do sul
/
Brasil
/
El salvador
Idioma:
En
Revista:
Rev. IMIP
Ano de publicação:
2000
Tipo de documento:
Article