Impact of HPV infection on the development of head and neck cancer
Braz. j. med. biol. res
; 46(3): 217-226, 15/mar. 2013. graf
Article
em En
| LILACS
| ID: lil-670893
Biblioteca responsável:
BR1.1
ABSTRACT
Human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) is considered to be a distinct clinical entity with better prognosis than the classical tobacco- and alcohol-associated tumors. The increasing incidence of this neoplasia during the last decades highlights the need to better understand the role of HPV in the development of these cancers. Although the proportion of HNSCC attributed to HPV varies considerably according to anatomical site, overall approximately 25% of all HNSCC are HPV-DNA positive, and HPV-16 is by far the most prevalent type. In this review we discuss the existing evidence for a causal association between HPV infection and HNSCC at diverse anatomical head and neck subsites.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Carcinoma de Células Escamosas
/
Infecções por Papillomavirus
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Neoplasias de Cabeça e Pescoço
Tipo de estudo:
Etiology_studies
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Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Braz. j. med. biol. res
Ano de publicação:
2013
Tipo de documento:
Article
/
Project document