[Irreversible airflow limitation in asthmatics].
Arerugi
; 47(12): 1258-63, 1998 Dec.
Article
em Ja
| MEDLINE
| ID: mdl-10028720
ABSTRACT
To evaluate irreversible airflow limitation in asthmatics, we studied 168 patients admitted to our hospital with acute exacerbation of asthma. All patients were given intravenous methylprednisolone for at least 7 days to maximum 14 days and the best of PEF (% of predicted) was evaluated. In all subjects, the best of PEF showed significant correlations with both the patients' age (r = -0.411, p < 0.0001) and the duration of asthma (r = -0.494, p < 0.0001). A significant correlations between the best of PEF and the duration of asthma were also observed in both patients over 60 years old (r = -0.157, p < 0.0001) and non-smokers (r = -0.568, p < 0.0001). We conclude that asthma may develop irreversible airflow limitation in itself and the degree of impairment of lung function correlated with the duration of the disease.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Asma
/
Pico do Fluxo Expiratório
Tipo de estudo:
Etiology_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ja
Revista:
Arerugi
Ano de publicação:
1998
Tipo de documento:
Article