Rats of the genus Rattus are reservoir hosts for pathogenic Bartonella species: an Old World origin for a New World disease?
J Infect Dis
; 180(1): 220-4, 1999 Jul.
Article
em En
| MEDLINE
| ID: mdl-10353885
ABSTRACT
Bartonella species were isolated from the blood of 63 of 325 Rattus norvegicus and 11 of 92 Rattus rattus from 13 sites in the United States and Portugal. Infection in both Rattus species ranged from 0% (e.g., 0/87) to approximately 60% (e.g., 35/62). A 337-bp fragment of the citrate synthase (gltA) gene amplified by polymerase chain reaction was sequenced from all 74 isolates. Isolates from R. norvegicus were most similar to Bartonella elizabethae, isolated previously from a patient with endocarditis (93%-100% sequence similarity), followed by Bartonella grahamii and other Bartonella species isolated from Old World rodents (Clethrionomys species, Mus musculus, and Rattus species). These data suggest that Rattus species are a reservoir host for pathogenic Bartonella species and are consistent with a hypothesized Old World origin for Bartonella species recovered from Rattus species introduced into the Americas.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bartonella
/
Infecções por Bartonella
/
Reservatórios de Doenças
/
Muridae
Limite:
Animals
País/Região como assunto:
America do norte
/
Europa
Idioma:
En
Revista:
J Infect Dis
Ano de publicação:
1999
Tipo de documento:
Article