Inhibition of pristane-induced peritoneal plasmacytoma formation.
Curr Top Microbiol Immunol
; 246: 351-61; discussion 361-2, 1999.
Article
em En
| MEDLINE
| ID: mdl-10396075
ABSTRACT
While the mechanism of how Indo inhibits PCTGEN is not established, Several hypothetical explanations provide new potential experimental approaches. Indo may block production of cytokines such as Il-6 in accessory cells that are critical for B-cell growth, viability and maturation, or it may directly target B cells via PPAR-gamma receptors. The latter mode of action is described in other cell types but not yet defined in B cells.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Peritoneais
/
Plasmocitoma
Limite:
Animals
Idioma:
En
Revista:
Curr Top Microbiol Immunol
Ano de publicação:
1999
Tipo de documento:
Article