[Multiple myeloma presenting as massive ascites].
Rinsho Ketsueki
; 40(6): 515-7, 1999 Jun.
Article
em Ja
| MEDLINE
| ID: mdl-10422291
ABSTRACT
Ascites is a rare complication of multiple myeloma. We report a case of multiple myeloma with peritoneal involvement. An 80-year-old woman was admitted to our hospital because of massive ascites. Laboratory findings included an Hb of 7.8 g/dl, IgA of 2,160 mg/dl, and CA125 of 942 IU/ml. Immunoelectropheresis analysis detected a monoclonal component of IgA lambda in serum, and of BJP lambda in urine. Bone marrow aspirtion revealed normal cellularity with 32.7% atypical plasma cells. The ascites was characterized by an exudate with numerous atypical plasma cells and elevated IgA and CA125 levels. The IL-6 level was 22 pg/ml and 79 pg/ml in serum and ascites, respectively. A diagnosis of IgA lambda multiple myeloma with peritoneal involvement was made. Chemotherapy consisting of melphalan and prednisolone reduced the serum IgA and CA125 levels markedly, and alleviated the patient's ascites.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ascite
/
Mieloma Múltiplo
Limite:
Aged
/
Aged80
/
Female
/
Humans
Idioma:
Ja
Revista:
Rinsho Ketsueki
Ano de publicação:
1999
Tipo de documento:
Article