Clinical impact of upper gastrointestinal tract injuries in glyphosate-surfactant oral intoxication.
Hum Exp Toxicol
; 18(8): 475-8, 1999 Aug.
Article
em En
| MEDLINE
| ID: mdl-10462358
ABSTRACT
Fifty patients with glyphosate-surfactant oral ingestion were studied with upper gastrointestinal (UGI) endoscopic grading using Zargar's modified grading system for mucosal corrosive injury. Esophageal injury was seen in 68% of the patients, gastric injury in 72%, and duodenal injury in 16%. There were no grade 3 injuries. The upper gastrointestinal tract injuries caused by glyphosate-surfactant were minor in comparison with those by other strong acids. The WBC count, amount of glyphosate-surfactant ingested, length of hospital stay and the occurrence of serious complications increased markedly in the group which had grade 2 esophageal injuries. Thus, the severity of the esophageal injuries may be a prognostic factor for the patient with glyphosate-surfactant ingestion. The UGI endoscopy may be indicated for grading esophageal injury in patients who have ingested glyphosate-surfactant in amounts greater than 100 ml. Physicians should pay more attention to the patients with grade 2 or 3 esophageal injuries to prevent serious complications and to provide aggressive supportive care.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças do Esôfago
/
Esôfago
/
Glicina
/
Herbicidas
Tipo de estudo:
Prognostic_studies
Limite:
Adult
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Aged
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Aged80
/
Female
/
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Hum Exp Toxicol
Ano de publicação:
1999
Tipo de documento:
Article