In situ hybridization-theory and practice.
Mol Diagn
; 4(3): 169-83, 1999 Sep.
Article
em En
| MEDLINE
| ID: mdl-10553018
ABSTRACT
In situ hybridization is a technique to determine and localize target nucleic acids in morphologically preserved tissue sections. Recent advances in methods have greatly increased the sensitivity of the technique, and it is currently possible to detect extremely few copies of any given target sequence with nonisotopic methods. In this teaching review, we integrate theoretical background, technical considerations, and guidelines for usage for this important component of molecular diagnosis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hibridização In Situ
Tipo de estudo:
Diagnostic_studies
/
Guideline
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Mol Diagn
Ano de publicação:
1999
Tipo de documento:
Article