The pathogenesis of Acanthamoeba keratitis.
Microbes Infect
; 1(6): 437-43, 1999 May.
Article
em En
| MEDLINE
| ID: mdl-10602676
ABSTRACT
Free-living amoebae of the genus Acanthamoeba produce a progressive, blinding infection of the corneal surface. The pathogenesis of Acanthamoeba keratitis involves parasite-mediated cytolysis and phagocytosis of corneal epithelial cells and induction of programmed cell death. Acanthamoeba spp. elaborate a variety of proteases which may facilitate cytolysis of the corneal epithelium, invasion of the extracellular matrix, and dissolution of the corneal stromal matrix.
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Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Acanthamoeba
/
Ceratite por Acanthamoeba
Tipo de estudo:
Etiology_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Microbes Infect
Ano de publicação:
1999
Tipo de documento:
Article