A particularly aggressive combined glucagonoma and gastrinoma syndrome.
Eur J Gastroenterol Hepatol
; 11(12): 1417-9, 1999 Dec.
Article
em En
| MEDLINE
| ID: mdl-10654804
ABSTRACT
Duodeno-pancreatic biochemically polyfunctional endocrine tumour is a well known entity. Usually, only one hormone is responsible for the clinical features. We report a case of aggressive combined glucagonoma and gastrinoma tumour without metastases, causing respectively diabetic ketoacidosis and fulminant peptic ulcer, and death. Occasional patients can present with clinical features of both glucagonoma and gastrinoma. Diabetic patients exhibiting migratory skin lesions should be suspected of glucagonoma. In addition, a multidisciplinary approach to such patients including dermatologists, surgeons, radiologists and endoscopists is mandatory.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Pancreáticas
/
Gastrinoma
/
Glucagonoma
/
Neoplasias Primárias Múltiplas
Tipo de estudo:
Etiology_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Eur J Gastroenterol Hepatol
Ano de publicação:
1999
Tipo de documento:
Article