Murine models of inflammation: role of CD23.
Allergy
; 55 Suppl 61: 21-6, 2000.
Article
em En
| MEDLINE
| ID: mdl-10919501
ABSTRACT
The role of IgE in eosinophil recruitment and bronchial hyperresponsiveness has been extensively studied with murine models of inflammation. Many investigators using various knockout models have clearly shown that both IgE-dependent and -independent pathways play a role in eosinophil recruitment and bronchial hyperresponsiveness after allergen challenge, illustrating the complexity of airways inflammation. The expression of this response is likely to involve many interacting pathways, and it will be a considerable challenge to determine key points within these pathways that will yield novel targets for future therapeutic strategies.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hiper-Reatividade Brônquica
/
Receptores de IgE
/
Inflamação
Limite:
Animals
Idioma:
En
Revista:
Allergy
Ano de publicação:
2000
Tipo de documento:
Article