CD5+ immunophenotype in the bone marrow but not in the peripheral blood in a patient with hairy cell leukemia.
Acta Haematol
; 103(4): 210-3, 2000.
Article
em En
| MEDLINE
| ID: mdl-11014896
ABSTRACT
We report the case of a patient with rare CD5+ hairy cell leukemia, which was unusual, as there was also a discrepancy between the bone marrow and peripheral blood immunophenotypes. We propose that some degree of maturation within the malignant clone and the predominance of more mature CD5- hairy cells in the peripheral blood can explain this observation. The patient was treated with a conventional course of cladribine (2'-chlorodeoxyadenosine) and achieved complete remission. We conclude that the unusual CD5+ immunophenotype of this patient did not affect prognosis or change the response to standard therapy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Medula Óssea
/
Leucemia de Células Pilosas
/
Antígenos CD5
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Acta Haematol
Ano de publicação:
2000
Tipo de documento:
Article