Convenient synthesis of optically active 2,2,2-trifluoro-1-phenylethylamine.

Kato, K; Gong, Y; Saito, T; Kimoto, H

Kato, K; Gong, Y; Saito, T; Kimoto, H.

Afiliação

Kato K; Department of Chemistry, National Industrial Research Institute of Nagoya, Hirate-cho, Kita-ku, Nagoya 462-8510, Japan. ktykato@nirin.go.jp

Enantiomer ; 5(5): 521-4, 2000.

Article em En | MEDLINE | ID: mdl-11143816

ABSTRACT

ABSTRACT

Amination of aryl trifluoromethyl ketones with ammonium formate readily gave racemic 2,2,2-trifluoro-1-arylethylamines in good yields. Resolution of 2,2,2-trifluoro-1-phenylethylamine was carried out with the Pseudomonas fluorescens lipase via enantioselective alcoholysis of its chloroacetamide.

Buscar no Google

Imprimir

XML

PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Enantiomer Ano de publicação: 2000 Tipo de documento: Article

Buscar no Google

Imprimir

XML

PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Enantiomer Ano de publicação: 2000 Tipo de documento: Article