Convenient synthesis of optically active 2,2,2-trifluoro-1-phenylethylamine.
Enantiomer
; 5(5): 521-4, 2000.
Article
em En
| MEDLINE
| ID: mdl-11143816
ABSTRACT
Amination of aryl trifluoromethyl ketones with ammonium formate readily gave racemic 2,2,2-trifluoro-1-arylethylamines in good yields. Resolution of 2,2,2-trifluoro-1-phenylethylamine was carried out with the Pseudomonas fluorescens lipase via enantioselective alcoholysis of its chloroacetamide.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Enantiomer
Ano de publicação:
2000
Tipo de documento:
Article